NSAID-Induced Mucosal Injury: Analysis of Gastric Toxicity with New Generation NSAIDs: Ulcerogenicity Compared with Ulcer Healing

نویسندگان

  • Fred Halter
  • K.D. Rainsford
  • Steven P. Sirko
  • Adrian Schmassmann
چکیده

Introduction: Some non-steroidal anti-inflammatory drugs (NSAIDs) delay healing of experimental gastric ulcers. The two experimental NSAIDs tebufelone and nitrofenac exert relatively low ulcerogenicity in various animal models compared with conventional NSAIDs. In addition, it has been reported that nitrofenac accelerates experimental acute ulcer healing. However, the effects of these new NSAIDs in a reliable chronic ulcer model has not been fully established.

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عنوان ژورنال:
  • The Yale Journal of Biology and Medicine

دوره 70  شماره 

صفحات  -

تاریخ انتشار 1997